Dapoxetine 60mg is a medication primarily used for the treatment of premature ejaculation (PE) in men aged 18 to 64 years old. PE is a common sexual dysfunction characterized by uncontrollable ejaculation either before or shortly after sexual penetration, causing distress and relationship problems. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), was originally developed as an antidepressant. However, due to its rapid absorption and elimination from the body, it was found to be more suitable for the treatment of PE.

Mechanism of Action:

Dapoxetine works by inhibiting the serotonin transporter, which leads to an increase in serotonin levels in the synaptic cleft. Serotonin is a neurotransmitter involved in regulating mood, emotions, and ejaculatory reflex. By increasing serotonin levels, dapoxetine helps to delay ejaculation and improve control over ejaculation. you should try super vidalista

Clinical Studies:

Numerous clinical trials have demonstrated the efficacy and safety of dapoxetine in the treatment of PE. One randomized, double-blind, placebo-controlled study published in the New England Journal of Medicine found that men treated with dapoxetine experienced a significant increase in the time to ejaculation compared to those who received a placebo. Similar results were reported in other trials, confirming dapoxetine's effectiveness in prolonging intravaginal ejaculation latency time (IELT) and improving overall sexual satisfaction.

Dosage and Administration:

Dapoxetine is typically taken orally, with or without food, one to three hours before anticipated sexual activity. The recommended starting dose is 30mg, which can be increased to 60mg if necessary. It is important to follow the prescribed dosage and instructions provided by a healthcare professional to achieve optimal results while minimizing the risk of adverse effects.